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Study Comparing Three Doses of MDMA Along With Psychotherapy in Veterans With Posttraumatic Stress Disorder

CompletedRegisteredCTG

Randomized, double-blind, dose-comparison Phase II study (n=26) testing 30 mg, 75 mg, and 125 mg MDMA HCl plus psychotherapy in veterans with chronic PTSD.

Details

Participants received preparatory non-drug therapy sessions then two blinded eight-hour MDMA-assisted therapy sessions (125 mg group received a third open-label session); supplemental half-dose given 1.5–2.5 hours after initial dose when agreed.

Outcomes include PTSD and depression symptoms, quality of life, posttraumatic growth, vital signs and adverse events assessed acutely and at follow-ups up to 12 months.

Topics:PTSD

Registry

Registry linkNCT01211405