Testing the Effectiveness of Cognitive Training... — Clinical Trial Details

Phase NA interventional

Randomized, quadruple Blind

Randomised, quadruple-blind, parallel-group study in patients receiving clinical esketamine comparing eight sessions of web-based cognitive training versus sham training; primary aim is improved depressive symptoms.

Intervention delivered remotely via computer; results could support scalable adjunctive strategies to augment esketamine treatment for depression.

Study Protocol

Preparation

sessions

Dosing

sessions

Western Psychiatric Institute and Clinic — Pittsburgh, Pennsylvania, United States

Any patient aged 18-80 in the esketamine clinic in the Center for Interventional Psychiatry. The clinic's extensive screening and eligibility criteria for esketamine treatment will not be altered in any way, other than imposing the study-specific age range and the two exclusion criteria below.

1. Patients who do not expect to remain located in the Pittsburgh area for a minimum of 1 month beyond study enrollment.
2. Patients who, in the judgment of the esketamine clinical medical director, show signs of intellectual disability, developmental disability, and/or cognitive impairment (including age-related cognitive decline) of a sufficient degree to interfere with engagement in any study procedure.

Start: 2023-02-14

End: 2025-08-01

Company

Product

Legal

Testing the Effectiveness of Cognitive Training Among Depressed Patients Receiving Esketamine Treatment

Detailed Description

Study Protocol

Preparation

Dosing

Locations

Integration

Therapeutic Protocol

Study Arms & Interventions

Cognitive Training

Interventions

Sham Training

Interventions

Participants

Inclusion Criteria

Exclusion Criteria

Study Details

Study Team

Sponsors & Collaborators