Start
•
Completion

The NeXT Study

CompletedResults publishedRegisteredCTG

This naturalistic observational study (n=225) investigates possible neurotoxic effects of recreational MDMA (ecstasy) on the human brain using imaging and cognitive measures.

Details

Prospective and retrospective components assess causality, course and clinical relevance of MDMA-related neurotoxicity. Cohorts include high-risk MDMA-naïve individuals followed for incident use, retrospectively selected exposed/unexposed participants, and a cross-sectional group with varied drug histories.

Outcomes include neuroimaging (SPECT, 1H-MRS, fMRI, perfusion MRI) and clinical measures of memory, mood and personality, controlling for confounders.

Topics:Neuroimaging & Brain Measures

Registry

Registry linkNCT00235768