The Role of Personal Experience for the... — Clinical Trial Details

Inclusion Criteria:
Participation in the SÄPT therapist training (medical doctors and psychologists)
Age 27 years or older
Sufficient understanding of the German language
Understanding of procedures and risks associated with the study
Willing to adhere to the protocol and signing of the consent form
Willing not to operate heavy machinery (including driving cars) within 24 hours after substance administration
Women of childbearing potential required to use effective contraception (oral, injected or implanted hormonal methods; IUD/IUS; barrier methods with spermicide) at least one month before and after each study substance intervention, and to take a urine pregnancy test at screening and before every study substance intervention
Men required to use contraceptive methods in the month after each study substance intervention and to inform partner(s) about study participation.

Exclusion Criteria:
Previous significant adverse response to a hallucinogenic drug
Significant medical condition rendering volunteers unsuitable for participation (e.g., impaired kidney or liver function, heart disease including uncontrolled hypertension or hypotension)
Strong underweight (<45 kg)
Current major psychiatric disorder (including personality disorder and suicidality) and/or previous psychotic or bipolar disorder
Psychotic disorder or bipolar disorder in first-degree relatives
Use of medication that may interfere with the effects of the study medication; willingness to discontinue medications with an appropriate washout (typically ≥5 half-lives, ~3–7 days) if judged acceptable by investigator
Women excluded during pregnancy or breastfeeding
Participation in another clinical trial currently or within the last 30 days

The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training (TherPsySE)