Tolerance and Potential Synergistic Effect of the Combination of Intranasal Esketamine and Non-selective MAOI (ESKETAM)

Published data on combinations of ketamine/esketamine with MAOIs are sparse and to our knowledge no data exist for intranasal esketamine; this study shares clinical experience from a specialised centre.

Retrospective case-only series of 13 adults treated with intranasal esketamine between 2018-01-01 and 2022-03-01 assessing tolerability and potential synergistic effects when combined with non-selective MAOIs; data reuse required patient consent.