Compound Profile

Placebo

Explore the clinical and pharmacological profile for Placebo, including current research trials and known mechanisms of action.

Pharmacology & Mechanism of Placebo

Detailed pharmacological information is currently being assembled by our research team.

Quick Facts

  • Highest PhasePhase III
  • Key IndicationsMajor Depressive Disorder (MDD), Treatment-Resistant Depression (TRD)

Connected Research

Recent clinical trials and academic literature investigating Placebo.

Recent Clinical Trials

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Not yet recruitingPhase III

Comparison of Intranasal Ketorolac and Intranasal Ketamine in Digital Nerve Block Pain

RecruitingPhase III

A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder (AVENUE)

CompletedPhase I

A Single dose safety and tolerability study of oral noribogaine in healthy volunteers; A single centre, double blind, randomised, placebo controlled, parallel group, ascending single dose, safety and tolerability, pharmacokinetic and pharmacodynamic study of oral noribogaine in healthy participants

CompletedPhase I

A single centre, double blind, randomised , parallel group, ascending single and multiple dose, safety and tolerability, pharmacokinetic and pharmacodynamic study of oral ketamine in healthy volunteer and patients with a history of depression or anxiety cohorts.

WithdrawnPhase I

Single dose ketamine pharmacokinetic-pharmacodynamic relationships in healthy volunteers

WithdrawnPhase I

A single centre, double blind, randomised, parallel group, single dose signal study of R-107 in particpants with DSM-5 specific phobia, to spiders.

Recent Academic Papers

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Time-resolved Neural and Experience Dynamics of Medium- and High-dose N,N-Dimethyltryptamine

Published
Journal
Journal of Cognitive Neuroscience

Microdosing psychedelics and its effect on creativity: Lessons learned from three double-blind placebo controlled longitudinal trials

Published
Journal
Neuropsychopharmacology

Psilocybin’s effect on human brain synaptic plasticity

Published
Journal
Research Square

The effect of methamphetamine and 3,4-methylenedioxymethamphetamine on peripheral endocannabinoid concentrations: a study in healthy adults

Published
Journal
Psychopharmacology

Meditation, psychedelics, and brain connectivity: A randomized controlled resting-state fMRI study of N,N-dimethyltryptamine and harmine in a meditation retreat

Published
Journal
Imaging Neuroscience

The empathogen 3,4-methylenedioxymethamphetamine, but not methamphetamine, increases feelings of global trust

Published
Journal
Journal of Psychopharmacology