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Yale University

Also known as: Yale School of Medicine, Yale University School of Medicine, Yale Department of Psychiatry, Yale University Department of Psychiatry, Yale-New Haven Hospital, Yale University

Data updated

21 Trials

In 2016, the 'Yale Psychedelic Science Group' was established as a forum where clinicians and scholars from across Yale can learn about and discuss the rapidly re-emerging field of psychedelic science and therapeutics in an academically rigorous manner. Research with psychedelics is also underway at Yale School of Medicine. A recent study at the university found that a single dose of psilocybin can cause structural changes in the brain that counteract symptoms of depression.

Academic Research

0 papers

Published Papers

0

Trial Involvement

21

Distinct Focus Topics

0

Latest Publication

Unknown

Government funding received

2 grants

VA — MDMA-assisted therapy for PTSD + alcohol use disorder in veterans

2024–2029

First VA-funded psychedelic study. VA researchers affiliated with Brown University and Yale University evaluate MDMA-assisted therapy for veterans with both PTSD and alcohol use disorder. $1.5M over five years. Marks the first time since the 1960s the VA has funded research on psychedelic compounds. Attributed here to Yale (Brown isn't in the Blossom stakeholder set).

Source

NIMH K-award — Psilocybin for treatment-resistant OCD (Kelmendi)

2021

First NIMH grant for a psychedelic research investigation since the 1960s. NIH career-development award to Benjamin Kelmendi, MD (Yale School of Medicine) for pilot psilocybin treatment of refractory OCD. Amount ≈$800K.

Source

Ecosystem

3 connections

Philanthropic Funders

Carey Turnbull

Support for research into psilocybin for OCD and headache disorders

Jan 1, 2018

undisclosed

Carey Turnbull Wears Many Hats as a Donor and Investor
Carey and Claudia Turnbull Family Foundation

Assisted the founding of Yale University's psilocybin research program

Jan 1, 2020

undisclosed

Carey Turnbull - Heffter Research Institute
Heffter Research Institute

Psilocybin treatment for obsessive-compulsive disorder (OCD)

Jan 1, 2022

undisclosed

Heffter Research Institute 2022 Newsletter

Research journey

Built from the 47 trials Yale University has sponsored, placed at the date each one started.

Clinical trial history47 sponsored trials · 6 lanes · 1 not yet startedtoday20092013201720212025Ketamine22 trialsPhase 2 · Bipolar DisorderPhase 4 · MDDTrialPhase 2 · SuicidalityPhase 2/3 · MDDPhase 3 · TRDPsilocybin14 trialsPhase 1 · Headache Disord…Other studies5 trialsDepressive DisordersEsketamine3 trialsPhase 3 · TRDDMT2 trials · Phase 12 other compoundsMDMA · Salvia DivinorumEach dot is a trial, placed at its start date. Hover a dot for what it tests and how far it got.

Featured in topic journeys

Clinical research timelines that include a curated milestone from Yale University.

Quick Facts

Type
academic
HQ
United States
Website
Visit

Research Landscape

What the registered trials Yale University sponsors or participates in look like when you line them up. Counts come from Blossom’s trial records as of August 2026.

How fast is Yale University research growing?

Sourced

Registered trials by recorded study-start year; 2 earlier trials began before 2012. Click a year for the running total.

6trials began in 2024

+50% vs 2023

38 started by 2024

Browse trials

Don't read as total research effort: only registered trials with a recorded start date are counted (48 of 48 tracked). Recent years under-count because of registration lag; striped bars are still filling in or are planned starts.

What's live right now, and what stopped?

Sourced

Registry status of all 48 Yale University trials Blossom tracks. Orange marks trials recruiting or opening.

Recruiting or opening
1429%
Underway, not recruiting
48%
Completed
2144%
Stopped early
919%

Don't read stopped trials as failures: trials end early for funding, recruitment, and strategy reasons too. Status is as last synced from the registry; some 'recruiting' trials may already have finished.

Which conditions does Yale University run trials on?

Sourced

Trials per primary indication. Orange marks the largest research focus.

Don't read shares as adding to 100%: a trial with several primary indications counts once per indication. Trial volume signals research attention, not evidence quality.

Which compounds appear in Yale University trials?

Sourced

Trials per compound. Orange marks the most-studied compound.

Don't read shares as adding to 100%: a trial testing several compounds counts once per compound, and placebo comparator arms are not shown. Trial volume signals research attention, not evidence quality.

Sponsored Trials

20
Not yet recruitingI

The Effects of Psilocybin on Social Connectedness

Start Date
Compounds
Placebo, Psilocybin
Not yet recruitingI

Psilocybin Microdosing on Cognition, Mood and Quality of Life

Start Date
Compounds
Psilocybin, Placebo
RecruitingII

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

Start Date
Compounds
Psilocybin
Not yet recruitingII

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

Start Date
Compounds
Psilocybin, Placebo
RecruitingII

MDMA in Borderline Personality Disorder (MDMA in BPD)

Start Date
Compounds
MDMA
RecruitingI

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Start Date
Compounds
DMT, Placebo
CompletedNA

Psychedelic Virtual Reality

Start Date
RecruitingI

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Start Date
Compounds
Psilocybin
RecruitingI

Mechanistic Studies of Psilocybin in Headache Disorders

Start Date
Compounds
Psilocybin, Placebo
RecruitingIII

PCORI Comparative Effectiveness Study-Esketamine (Spravato) Vs. Ketamine-Equivalence Study

Start Date
Compounds
Ketamine, Esketamine
TerminatedNA

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Start Date
Compounds
Placebo
RecruitingI

Open-Label Psilocybin

Start Date
Compounds
Psilocybin
TerminatedNA

Role Of Non-Specific Effects in The Treatment of Depression With Esketamine (ROSETTE)

Start Date
CompletedNA

Using Virtual Reality to Control the Audio-visual Inputs During Ketamine/Esketamine Treatment

Start Date
WithdrawnI

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD

Start Date
Compounds
MDMA, Placebo
RecruitingNA

The OBSERVE Protocol

Start Date
Compounds
Ketamine, Esketamine
Enrolling by invitationNA

Long Term Follow Up KET-PD

Start Date
Compounds
Ketamine, Placebo
RecruitingII

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Start Date
Compounds
Ketamine
Active not recruitingI

Effects of Repeated Psilocybin Dosing in OCD

Start Date
Compounds
Psilocybin
RecruitingII

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Start Date
Compounds
Ketamine, Placebo

Where this pipeline sits in the field

Yale University runs late-stage trials that Blossom ranks by how soon a catalyst is expected, alongside every other Phase 2 and Phase 3 study in the field.

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Collaborated Trials

1

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