This cross-species experimental study (n=21 humans; n=10 rats) finds that psilocin (18.2mg/70kg for humans; 0.3mg/kg for rats) impairs the ability to distinguish between static and moving images in both humans and rats. In humans, the impairment aligns with psilocin plasma levels and self-reported hallucination intensity. In rats, the effect is specific to motion perception, providing the first evidence of psilocin-induced visual distortions across species.
- Published
- Journal
- Biological Psychiatry
- Authors
- Brunovský, M., Horáček, J., Janečková, L., Kelemen, E., Korčák, J., Koudelka, V., Kuchař, M., Nekovářová, T., Nikolič, M., Páleníček, T., Šíchová, K., Syrová, K., Tesař, M., Tylš, F., Vejmola, C., Viktorin, V., Viktorinová, M.