Academic Journal

Biological Psychiatry

37 Papers Indexed in Blossom

Published Papers

Open Accessindividual

Cross-Species Evidence for Psilocin-Induced Visual Distortions: Apparent Motion Is Perceived by Both Humans and Rats

This cross-species experimental study (n=21 humans; n=10 rats) finds that psilocin (18.2mg/70kg for humans; 0.3mg/kg for rats) impairs the ability to distinguish between static and moving images in both humans and rats. In humans, the impairment aligns with psilocin plasma levels and self-reported hallucination intensity. In rats, the effect is specific to motion perception, providing the first evidence of psilocin-induced visual distortions across species.

Published
Journal
Biological Psychiatry
Authors
Brunovský, M., Horáček, J., Janečková, L., Kelemen, E., Korčák, J., Koudelka, V., Kuchař, M., Nekovářová, T., Nikolič, M., Páleníček, T., Šíchová, K., Syrová, K., Tesař, M., Tylš, F., Vejmola, C., Viktorin, V., Viktorinová, M.
Open Accessindividual

Comparing neural correlates of consciousness: from psychedelics to hypnosis and meditation

This comparative neuroimaging study (n=107) compares the neural correlates of two pharmacological methods, psilocybin (n=23) and LSD (n=25), and two non-pharmacological methods, hypnosis (n=30) and meditation (n=29), in inducing altered states of consciousness (ASC). The results reveal distinct connectivity patterns associated with pharmacological and non-pharmacological interventions, predictability at an individual level, and unique behavioural-neural relationships between psilocybin and LSD, all contributing to a broader understanding of the mechanisms of ASC and their potential therapeutic applications in psychiatric disorders.

Published
Journal
Biological Psychiatry
Authors
Rieser, N. M.
Open Accessindividual

Effective-connectivity of thalamocortical interactions following d-amphetamine, LSD, and MDMA administration

This re-analysis of a double-blind, placebo-controlled, crossover study (n=25) investigated the effects of LSD, MDMA and dextroamphetamine on brain measures (thalamocortical and corticothalamic interactions in resting-state fMRI data). Compared to placebo, all three substances increased the effective-connectivity from the thalamus to specific unimodal cortices while reducing their influence on the thalamus, revealing increased bottom-up and decreased top-down information flow; LSD uniquely increased effective-connectivity to both unimodal and transmodal cortices.

Published
Journal
Biological Psychiatry
Authors
Avram, M., Borgwardt, S., Holze, F., Korda, A., Ley, L., Liechti, M. E., Müller, F., Preller, K. H., Razi, A., Rogg, H., Vizeli, P.

Quick Facts

Papers Indexed
37
h-Index
367
Open Access
No
Publisher
Elsevier
Country
United States
Website
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