This double-blind placebo-controlled study (n=25) assessed the effects of LSD on metabolic pathways associated with neural plasticity, to gain insight into the relationship between neural plasticity, ageing and LSD-induced cognitive gains in both humans and rodents. LSD treatment in humans (50μg) enhanced performance in a visuospatial memory task, and in a novel object recognition task in rodents indicating that LSD has nootropic effects.
- Published
- Journal
- Experimental Neurology
- Authors
- Ornelas, I. M., Cini, F. A., Wießner, I., Marcos, E., De Araújo, D., Goto-Silva, L., Nascimento, J., Silva, S. R. B., Costa, M. N., Falchi, M., Olivieri, R., Palhano-Fontes, F., Sequerra, E., Martins-De- Souza, D., Feilding, A., Rennó-Costa, C., Tófoli, L. F., Rehen, S. K., Ribeiro, S., Dráulio De Araújo, Martins-De-Souza, D.