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Academic Journal

Human Psychopharmacology

8 Papers Indexed in Blossom

Published Papers

Paywallindividual

Clinical predictors of depressive symptom remission and response after racemic ketamine and esketamine infusion in treatment-resistant depression

In a randomised, double‑blind trial of single subanaesthetic infusions of racemic ketamine or esketamine in 61 people with treatment‑resistant major depressive disorder, higher baseline illness severity and a greater number of prior treatment failures predicted poorer outcomes. Specifically, more treatment failures and greater severity were associated with lower odds of remission at 7 days and reduced likelihood of response at 24 hours.

Published
Journal
Human Psychopharmacology
Authors
Jesus‐Nunes, A. P., Leal, G. C., Correia‐Melo, F. S., Vieira, F., Mello, R. P., Caliman‐Fontes, A. T., Echegaray, M. V. F., Marback, R. F., Guerreiro‐Costa, L. N. F., Souza‐Marques, B., Santos‐Lima, C., Souza, L. S., Bandeira, I. D., Kapczinski, F., Lacerda, A. L. T., Quarantini, L. C.
Paywallindividual

Ayahuasca may help to improve self-compassion and self-criticism capacities

A pre–post study of 45 volunteers found that participation in an ayahuasca ceremony was associated with significant medium-to-large improvements in self‑compassion, reductions in self‑criticism and increases in self‑reassurance within 24 hours. These exploratory results suggest ayahuasca may enhance well‑being and have therapeutic potential for negative affect, but larger controlled trials are required to confirm the effect.

Published
Journal
Human Psychopharmacology
Authors
Domínguez-Clavé, E., Soler, J., Elices, M., Franquesa, A., Enric Álvarez, |., Pascual, J. C.
Open Accessindividual

The chemical induction of synaesthesia

Surveying recreational users and developmental synaesthetes for 28 psychoactive drugs, the study found that serotonergic compounds—especially tryptamines and LSD—most frequently induce synaesthesia (commonly sound–colour), with induction rates clustering by drug class and similar patterns in controls and synaesthetes. The results support a serotonergic contribution to chemically induced synaesthesia, while also indicating individual susceptibility and possible involvement of non-serotonergic pathways.

Published
Journal
Human Psychopharmacology
Authors
Luke, D., Lungu, L., Friday, R., Terhune, D. B.
Paywallindividual

A qualitative descriptive analysis of effects of psychedelic phenethylamines and tryptamine

From in‑depth interviews with 39 adults who had used 36 different psychedelic phenethylamines and tryptamines, the study characterised common subjective effects across compounds. 2C‑B was described favourably and likened to MDMA and LSD, NBOMe was generally viewed unfavourably, DOx were criticised for their excessive 12–36 hour duration, and 4‑AcO‑DMT was reported to mimic psilocybin, information useful for education and harm reduction.

Published
Journal
Human Psychopharmacology
Authors
Palamar, J. J., Acosta, P.
Open Accessindividual

Genie in a blotter: A comparative study of LSD and LSD analogues’ effects and user profile

Using data from the Global Drug Survey, the authors found that users of LSD analogues (AL‑LAD, 1P‑LSD, ETH‑LAD)—most of whom had also used LSD—reported similar time‑to‑peak (~2 hr) and duration (~8 hr) but significantly weaker subjective effects (pleasurable high, strength, comedown, urge to reuse), lower value for money and lower perceived risk than LSD; many obtained analogues online and almost all used them orally. The paper recommends chemical confirmation and dose measurement in future studies to validate these self‑report findings.

Published
Journal
Human Psychopharmacology
Authors
Coney, L. D., Maier, L. J., Ferris, J. A., Winstock, A. R., Barratt, M. J.
Open Accessindividual

Measuring the subjective: revisiting the psychometric properties of three rating scales that assess the acute effects of hallucinogens

This study (n=158) examined the psychometric properties of three commonly used rating scales (MEQ, HRS, ARCI). The authors found only sparing agreement of their psychometric analyses with the theoretically proposed models of the scales.

Published
Journal
Human Psychopharmacology
Authors
Bouso, J. C., Pedrero-Pérez, E. J., Gandy, S.

Quick Facts

Papers Indexed
8
h-Index
87
Open Access
No
Publisher
Wiley
Country
United Kingdom
Website
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