This comprehensive review argues that hallucinogenic drugs can enhance fear extinction—by promoting neuroplasticity, tempering amygdala hyperreactivity and facilitating emotional engagement—and thus offer advantages over current first‑line treatments for fear‑related disorders. It highlights MDMA and ketamine as the most promising therapeutics to augment exposure therapy and examines the molecular mechanisms relevant to hallucinogen‑assisted psychotherapy.
- Published
- Journal
- Journal of Neuroscience Research
- Authors
- Glavonic, E., Mitic, M., Adzic, M.