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Journal of Traumatic Stress

2 Papers Indexed in Blossom

Published Papers

Open Accessindividual

Sleep Quality Improvements After MDMA-Assisted Psychotherapy for the Treatment of Posttraumatic Stress Disorder

In four randomised, double‑blind Phase 2 trials (n=63), 2–3 sessions of MDMA‑assisted psychotherapy significantly improved self‑reported sleep quality and produced larger reductions in PTSD symptoms than low‑dose/control MDMA, with sleep gains maintained at 12 months. At the primary endpoint CAPS‑IV scores fell by −34.0 versus −12.4 and PSQI total score changed by −3.5 versus +0.6 for active versus control (p = .003 for both).

Published
Journal
Journal of Traumatic Stress
Authors
Ponte, L., Jerome, L., Hamilton, S., Mithoefer, M. C., Yazar-Klosinski, B. B., Vermetten, E., Feduccia, A. A.
Open Accessmeta

Posttraumatic Growth After MDMA-Assisted Psychotherapy for Posttraumatic Stress Disorder

Pooled data from three Phase 2 triple‑blind crossover trials show that MDMA‑assisted psychotherapy (75–125 mg) produced significantly greater posttraumatic growth (Hedges’ g = 1.14) and larger PTSD symptom reductions (Hedges’ g = 0.88) at the primary endpoint versus placebo/low‑dose control. These gains persisted to 12‑month follow‑up—with higher PTG, lower symptom scores and 67.2% no longer meeting PTSD criteria—suggesting PTG may be a meaningful mechanism of treatment effect.

Published
Journal
Journal of Traumatic Stress
Authors
Gorman, I., Belser, A. B., Jerome, L., Hennigan, C., Shechet, B., Hamilton, S., Yazar-Klosinski, B., Emerson, A., Feduccia, A. A.

Quick Facts

Papers Indexed
2
h-Index
161
Open Access
No
Publisher
Wiley
Country
United States
Website
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