This synthesis article (2019) explains the gram-scale production of psilocybin in E. coli (a prokaryotic host), which is a 32-fold improvement over earlier techniques. However, it's still much more expensive than growing it in mushrooms/truffles.
- Published
- Journal
- Metabolic Engineering
- Authors
- Adams, A. M., Brinton, J. D., Enacopol, A. L., Jones, J. A., Monnier, C. S., Ramelot, T. A., Wei, Z.