This Perspective argues that classical psychedelics act as catalysts of neural plasticity by engaging diverse cellular and subcellular signalling pathways — interacting with stress and inflammation — which likely underpin their therapeutic effects. The authors contend that this mechanistic complexity both mirrors the heterogeneity of psychiatric disorders and reshapes our understanding of mood, behaviour and consciousness.
- Published
- Journal
- Molecular Biology of the Cell
- Authors
- Bement, W., Banks, M. I., Zahid, Z., Jones, N. T., Sultan, Z. W., Wenthur, C. J.