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Academic Journal

Neurobiology of Learning and Memory

2 Papers Indexed in Blossom

Published Papers

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Improving cognitive functioning in major depressive disorder with psychedelics: a dimensional approach

This theory-building literature review (2021) proposes a model that explains how psychedelics can reduce the negativity bias in depressed patients according to Research Domain Criteria (RDoC), a framework that investigates the underlying neurobiology of clinical symptoms across multiple levels of explanation. It is proposed that psychedelics improve depressive symptoms via a similar mechanism as the antidepressant vortioxetine, by stimulating neuroplasticity in the prefrontal cortex and the hippocampus, and decreasing negativity bias through the restoration of deficits in pattern separation.

Published
Journal
Neurobiology of Learning and Memory
Authors
Kuiperes, Z., Schreiber, R.
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Ketamine anesthesia enhances fear memory consolidation via noradrenergic activation in the basolateral amygdala

This animal study (n=206) investigated the effects of ketamine (125 mg/kg) on fearful memory consolidation associated with traumatic events and found that ketamine enhances the formation of these memories only when administered in close proximity to the trauma, partially via sympathetic stimulation which releases noradrenaline.

Published
Journal
Neurobiology of Learning and Memory
Authors
Morena, M., Colucci, P., Mancini, G. F., De Castro, V., Peloso, A., Schelling, G., Campolongo, P.

Quick Facts

Papers Indexed
2
h-Index
137
Open Access
No
Publisher
Elsevier
Country
United States
Website
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