In a three‑patient case series, self‑administered sub‑psychedelic (micro) doses of psilocybin produced robust analgesia and reduced reliance on conventional analgesics for chronic neuropathic pain, with minimal cognitive or somatic adverse effects. Effects were enhanced and sometimes prolonged by functional exercise, and repeated dosing suggested possible plasticity‑mediated cumulative benefit, warranting controlled investigation.
- Published
- Journal
- PAIN
- Authors
- Lyes, M., Yang, K. H., Castellanos, J. P., Furnish, T.