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Pharmacological Research

4 Papers Indexed in Blossom

Published Papers

Open Accessmeta

Mind over matter: the microbial mindscapes of psychedelics and the gut-brain axis

This review (2024) examines the potential role of the gut microbiome in mediating the effects of psychedelic drugs on behaviour. It argues that the current understanding of psychedelic mechanisms, focused primarily on serotonin 2A receptor agonism, is incomplete and needs to incorporate the gut microbiome and its (two-way) interactions with the brain.

Published
Journal
Pharmacological Research
Authors
Caspani, G., Ruffell, S. G. D., Tsang, WF., Netzband, N., Rohani-Shukla, C., Swann, J. R., Jefferies, W. A.
Open Accessmeta

The Integration of Classic Psychedelics into Current Substance Use Disorder Treatment Models

This review (2023) discusses the potential integration of classic psychedelic-assisted therapies (PAT) into current clinical practices for substance use disorders (SUDs). With promising results from initial studies, the authors suggest that classic psychedelic-assisted therapies could become legally available options for SUD patients in the future. The article outlines contemporary evidence-based treatments for SUDs and proposes that classic psychedelic-assisted therapies can be broadly compatible with existing mainstream SUD treatment paradigms, offering a new avenue for exploration in addressing these disorders.

Published
Journal
Pharmacological Research
Authors
Yaden, D. B., Berghella, A. P., Hendricks, P. S., Yaden, M. E., Levine, M., Rohde, J. S., Nayak, S., Johnson, M. W., Garcia-Romeu, A.
Open Accessmeta

Ibogaine - A legacy within the current renaissance of psychedelic therapy

This review (2023) gives an overview of research into ibogaine. It details animal studies and the human use of ibogaine in stopping addiction. Studies are few and far between, and clinical trials are only now being started.

Published
Journal
Pharmacological Research
Authors
Mash, D. C.
Open Accessindividual

The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors

This rat study (2016) found that LSD decreased the firing rate of dopamine neurons in the ventral tegmental area (VTA, in the midbrain) in rats at very high doses.

Published
Journal
Pharmacological Research
Authors
De Gregorio, D., Posa, L., Ochoa-Sanchez, R., Mclaughlin, R., Maione, S., Comai, S., Gobbi, G.

Quick Facts

Papers Indexed
4
h-Index
183
Open Access
Yes
Publisher
Elsevier
Country
United States
Website
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