This systematic review and meta-analysis of oral ketamine for major depression (10 studies; meta-analysis of three RCTs, N=161) found a significant antidepressant effect (SMD −0.75). The paper also summarises tolerability data but emphasises that the evidence base is small and further high-quality trials are needed.
- Published
- Journal
- Psychopharmacology Bulletin
- Authors
- Nuñez, N. A., Joseph, B., Pahwa, M., Seshadri, A., Prokop, L. J., Kung, S., Schak, K. M., Voort, J. L. V., Frye, M. A., Singh, B.