Outcome MeasureOther

TFI

Tinnitus Functional Index

1 Paper in Blossom

Outcome Data Across Studies

Reported results for TFI across 1 study with quantitative data.

Papers Using TFI

Paywallindividual

A proof-of-principle study of the short-term effects of 3,4-methylenedioxymethamphetamine (MDMA) on tinnitus and neural connectivity

This double-blind, randomised, controlled cross-over study (n=13) explores MDMA's (30-70mg) impact on tinnitus through behavioural and rs-fMRI assessments. No notable effects were observed at the lower dose. However, the 70 mg dose significantly reduced tinnitus annoyance and ignore ratings post-administration. Neurophysiological analysis revealed decreased connectivity in emotion and memory-related brain regions (hippocampal and amygdala) and increased connectivity in sensory processing and attention areas (right post-central gyrus, posterior and superior temporal gyrus, thalamus, and frontoparietal network) with MDMA versus placebo.

Published
Journal
International Journal of Neuroscience
Authors
Searchfield, G. D., Poppe, T. N. E. R., Durai, M., Jensen, M., Kennedy, M. A., Maggo, S., Miller, A. L., Park, J., Russell, B. R., Shekhawat, G. S., Spiegel, D., Sundram, F., Wise, K.

Quick Facts

Full Name
Tinnitus Functional Index
Domain
Other
Papers Indexed
1
Score Range
0–100
Interpretation
Lower = better
Unit
points
All Measures