Reducing the Harms of Nonclinical Psychedelics Use Through a Peer-Support Telephone Helpline
This data analysis study (n=884) examines the impact of a psychedelic helpline on mitigating risks associated with nonclinical psychedelic use. The findings suggest that 65.9% of callers experienced a de-escalation in psychological distress due to the helpline. Additionally, 29.3% reported they could have been harmed, 12.5% might have dialed 911, and 10.8% could have visited an emergency room had it not been for their interaction with the helpline, implying the helpline may prevent harmful outcomes and alleviate strain on emergency and medical services.
Abstract
Introduction
A resurgence of interest in the use of psychedelics for mental health and wellness has stimulated greater experimentation with psychedelics in society. Although clinical psychedelic trials protect research participants by offering a safe setting, thorough preparation, and containment during and after ingestion of psychedelic medicines, many try these substances without the benefit of these safeguards.
Materials and Methods
We analyzed data gathered from 884 callers to a psychedelic helpline to determine whether a helpline model could reduce the risks associated with nonclinical psychedelics use.
Results
In total, 65.9% of callers indicated that the helpline de-escalated them from psychological distress. If not for their conversation with the helpline, 29.3% of callers indicated they may have been harmed; 12.5% indicated that they may have called 911; and 10.8% indicated they may have gone to the emergency room.
Conclusion
The data suggest that access to a psychedelic helpline surrounding psychedelic experiences may avert harmful outcomes and offset the burden on emergency and medical services.
Research Summary of 'Reducing the Harms of Nonclinical Psychedelics Use Through a Peer-Support Telephone Helpline'
Introduction
Earlier research indicates that psychedelic-assisted therapy (PAT) delivered in clinical settings includes multiple safeguards — medical and psychological screening, preparatory sessions, supervised dosing, and postdosing integration — which aim to maximise therapeutic benefit and reduce risk. By contrast, many people now use psychedelics outside clinical settings where those protections are absent. The extracted text notes rising nonclinical use in recent years, citing survey data that show increased past-year use among young adults and middle-aged adults, and highlights that harms from nonclinical use tend to be psychological (for example, distress, panic, or risky behaviour during so-called "bad trips") rather than toxicological in nature. This study sets out to examine whether a peer-support telephone helpline can reduce risks associated with nonclinical psychedelics use. Specifically, Pleet and colleagues piloted an existing peer-support helpline to determine whether conversations with trained volunteers de-escalated callers in distress and might avert emergency service use or other harms in naturalistic psychedelic contexts.
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Study Details
- Study Typeindividual
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- APA Citation
Pleet, M. M., White, J., Zamaria, J. A., & Yehuda, R. (2023). Reducing the Harms of Nonclinical Psychedelics Use Through a Peer-Support Telephone Helpline. Psychedelic Medicine, 1(2), 69-73. https://doi.org/10.1089/psymed.2022.0017
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O’Mahony, B., Harrington, C., Harkin, A. et al. · Journal of Psychopharmacology (2026)
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