DMT

The psychedelic model of schizophrenia: the case of N,N-dimethyltryptamine

This review (1976) looks a the psychedelic model of schizophrenia, saying that DMT is a schizotonix that mimics symptoms of schizophrenia in healthy individuals. The authors conclude that more data are necessary to determine the validity of this theory.

Authors

  • Gillin, J. C.
  • Kaplan, J.
  • Stillman, R.

Published

American Journal of Psychiatry
meta Study

Abstract

The authors review the research on N,N-dimethyltryptamine (DMT) as a possible schizotoxin. DMT produces psychedelic effects when administered to normal subjects, the means are present to synthesize it in man, it has occasionally been found in man, and tolerance to its behavioral effects is incomplete. However, DMT concentrations have not been proven to differ significantly in schizophrenics and normal controls. Also, in vivo synthesis of DMT has not been convincingly demonstrated, and the psychological changes it produces do not closely mimic the symptoms of schizophrenia. The authors conclude that more data are necessary before the validity of this theory can be determined.

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Research Summary of 'The psychedelic model of schizophrenia: the case of N,N-dimethyltryptamine'

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Cited By (16)

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