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Home/Research/Ayahuasca/Equity and Ethics

Ayahuasca for Equity and Ethics

5 papers and 0 clinical trials exploring ayahuasca as a treatment for equity and ethics.

Compoundclassic psychedelic

Ayahuasca

Ayahuasca is a botanical decoction combining DMT with MAO-inhibiting harmala alkaloids, producing intense psychedelic effects lasting 3-6 hours. Clinical trials show rapid, large antidepressant effects from a single dose, with a favourable safety profile in controlled settings.

Full Ayahuasca profile
IndicationApproximately 1 in 4 adults experience mental health disorders annually worldwide.

Equity and Ethics

Equity and ethics in psychedelic research is a vital and complex topic, addressing the need for fair access and representation in clinical trials, as well as the stewardship of traditional knowledge. The involvement of Indigenous communities, who have historically used these substances, must be safeguarded against exploitation as the field matures.

Full Equity and Ethics profile

Academic Research

5 papers
Open Accessindividual

Mixed-methods analysis on psychedelic-augmented meditation experiences from a randomized controlled mindfulness retreat

This secondary analysis of a randomised controlled trial of DMT/harmine in experienced meditators found that meditation under DMT-harmine differed from placebo in its thematic and experiential profile while still sharing some semantic features. Using NLP-based analysis of phenomenological interviews, the study also suggested overlap between meditative and psychedelic states and highlighted the strong influence of context and spiritual framing on subjective experience.

Published
March 18, 2026
Journal
Scientific Reports
Authors
Schlomberg, J. T. T., Meling, D., Grylka, R., Vasella, E. A., Augustinovic, D., Scheidegger, M.
Paywallmeta

Overcoming epistemic injustices in the biomedical study of ayahuasca: Towards ethical and sustainable regulation

This commentary (2022) questions the epistemic authority of western medicine in over 30 years of research on ayahuasca. Ayahuasca has long been used by indigenous peoples in countries like Brazil, Peru and Colombia, and the researchers propose new approaches to maintain epistemically fair research and ensure these peoples traditional knowledge and biocultural heritage is maintained. Without adequate regulation, the rights of indigenous people, as well as the sustainability of the Amazon itself, face threat.

Published
January 6, 2022
Journal
Transcultural Psychiatry
Authors
Schenberg, E. E., Gerber, K.
Open Accessmeta

Ayahuasca Beyond the Amazon: the Benefits and Risks of a Spreading Tradition

This commentary (2010) examines how to integrate these spiritual healing rituals into contemporary Western concepts of psychological health and ethical conduct, and calls for an enforcement mechanism of accountability for monitoring the reputations of different ritual leaders to protect the community from predatory practices.

Published
December 1, 2010
Journal
Journal of Transpersonal Psychology
Authors
Trichter, S.
Paywallindividual

Ayahuasca in adolescence: a neuropsychological assessment

This study (n=80) evaluated the neuropsychology of adolescents who used ayahuasca in a religious context, compared to a matched control group of adolescents who did not use ayahuasca. There was no significant difference between the two groups on neuropsychological measures.

Published
June 1, 2005
Journal
Journal of Psychoactive Drugs
Authors
Doering-Silveira, E., Lopez, E., Grob, C. S., de Rios, M. D., Alonso, J. N., Tacla, C., Shirakawa, I., Bertolucci, P. H., da Silveira, D. X.
Paywallindividual

Ayahuasca in adolescence: Qualitative results

This retrospective survey (n=54) investigated the impact of religious Ayahuasca use on adolescents. The qualitative data shows that the teens using Ayahuasca religiously appeared not to differ from their non-ayahuasca-using peers. They were reported to be healthy, thoughtful, considerate, and bonded to their families and religious peers.

Published
June 1, 2005
Journal
Journal of Psychoactive Drugs
Authors
de Rios, M. D., Grob, C. S., Lopez, E., Alonso, J. N., Doering-Silveira, E., da Silveira, D. X.

Clinical Trials

0 trials

No clinical trials have been tagged with both Ayahuasca and Equity and Ethics yet.

Trials are continuously being added as new studies are registered.

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