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Home/Research/Mescaline/Bipolar Disorder

Mescaline for Bipolar Disorder

2 papers and 0 clinical trials exploring mescaline as a treatment for bipolar disorder.

CompoundPhenethylamine

Mescaline

A naturally occurring phenethylamine psychedelic found in certain cacti, investigated for its role in religious practice and psychiatric research.

Full Mescaline profile
Indication45 million worldwide

Bipolar Disorder

Bipolar disorder, characterised by extreme fluctuations in mood, is a complex mental health condition that affects approximately 45 million people worldwide. Current research on psychedelics as a potential treatment is limited due to concerns about inducing manic episodes, but emerging evidence, particularly regarding ketamine, suggests promise for alleviating depressive symptoms associated with the disorder.

Full Bipolar Disorder profile

Academic Research

2 papers
Open Accessmeta

Reconsidering evidence for psychedelic-induced psychosis: an overview of reviews, a systematic review, and meta-analysis of human studies

This systematic review (2024) and meta-analysis (s=131) examines the incidence of psychedelic-induced psychosis, focusing on individuals with schizophrenia. It finds an incidence of 0.002% in population studies, 0.2% in UCTs, and 0.6% in RCTs, with 3.8% of UCT participants with schizophrenia developing long-lasting psychotic symptoms. It also reports that 13.1% of those with psychedelic-induced psychosis later developed schizophrenia.

Published
November 27, 2024
Journal
Molecular Psychiatry
Authors
Sabé, M., Sulstarova, A., Glangetas, A., De Pieri, M., Mallet, L., Curtis, L., Richard-Lepouriel, H., Penzenstadler, L., Seragnoli, F., Thorens, G., Zullino, D., Preller, K., Böge, K., Leucht, S., Correll, C. U., Solmi, M., Kaiser, S., Kirschner, M.
Open Accessindividual

Psychedelics and mental health: a population study

This survey study that included psychedelics users (n=21.967, 13% of total) found no associations between psychedelics use and mental health outcomes. It even found a slightly lower rate of mental health problems for those who used psychedelics.

Published
August 19, 2013
Journal
PLOS ONE
Authors
Krebs, T. S., Johansen, P. ˚. Ø.

Clinical Trials

0 trials

No clinical trials have been tagged with both Mescaline and Bipolar Disorder yet.

Trials are continuously being added as new studies are registered.

Explore further

Search all Mescaline papers Search all Bipolar Disorder trials Full Mescaline profile Full Bipolar Disorder profile