Phenethylamine

Mescaline

A naturally occurring phenethylamine psychedelic found in certain cacti, investigated for its role in religious practice and psychiatric research.

Pharmacology & Mechanism of Mescaline

Detailed pharmacological information is currently being assembled by our research team.

Quick Facts

  • Highest PhasePhase I
  • Key IndicationsSafety & Risk Management
  • Primary Mechanism5-HT2A Agonist
  • Session Duration8-12 hours
  • OriginBotanical (Cacti) / Synthesised

Connected Research

Recent clinical trials and academic literature investigating Mescaline.

Recent Clinical Trials

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Unknown statusPhase IV

Comparing Mescaline Sodium Enteric-coated Tablets vs Morte-mescaline in the Treatment of Adult Lupus Nephritis

CompletedPhase I

Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of Consciousness

CompletedPhase I

Comparative Acute Effects of LSD, Psilocybin and Mescaline

Recent Academic Papers

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Pharmacokinetics, Pharmacodynamics, and Urinary Recovery of Oral Mescaline Hydrochloride in Healthy Participants

Published
Journal
Clinical Pharmacokinetics

Naturalistic psychedelic use and changes in depressive symptoms

Published
Journal
Journal of Affective Disorders

Health-related behavioral changes following the use of psychedelics in naturalistic settings

Published
Journal
Preventative Medicine Reports

‘Equal-unblinding’ meta-analysis of psychedelic therapy vs. antidepressants for the treatment of depression

Published
Journal
OSF Preprints

Insights on Psychedelics: A Systematic Review of Therapeutic Effects

Published
Journal
Neuroscience and Biobehavioral Reviews

Reconsidering evidence for psychedelic-induced psychosis: an overview of reviews, a systematic review, and meta-analysis of human studies

Published
Journal
Molecular Psychiatry