Patient-Centered Outcomes Research Institute
The Patient-Centered Outcomes Research Institute (PCORI) is a Washington, DC–based independent non-profit (501(c)(1)) created by the 2010 Affordable Care Act to fund comparative effectiveness research. PCORI awarded $12.6 million to Yale University researchers to directly compare IV racemic ketamine versus intranasal esketamine (Spravato) for treatment-resistant depression, and separately funded the ELEKT-D ketamine vs. ECT effectiveness trial conducted through the Cleveland Clinic Foundation.
Foundations & Philanthropy Snapshot
Grant-Making OrganizationsClassification
Public Charity / Non-Profit
Geography
Global
Coverage
Global
Last Verified
Apr 10, 2026
Funding Focus Areas
Support Types
Philanthropy Notes
Auto-backfilled baseline philanthropy profile from existing category tags and website. Manual enrichment recommended for recipient-level details.
Verification
Verified
Psychedelic Focus
Psychedelic-Adjacent Focus
Engagement Status
Active
Verification Notes
Verified against official PCORI funding opportunity pages.
Quick Facts
- Type
- Non-Profit
- HQ
- United States
- Website
- Visit