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A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years

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Phase I double-blind, placebo-controlled, randomised study (n=48) of very low-dose LSD (5, 10, 20 µg) or placebo given six times over 21 days in healthy volunteers aged 55–75.

Details

Randomised, quadruple-blind, parallel-group study comparing three very-low-dose LSD regimens (5, 10, 20 µg) to placebo; dosing on Study Days 1, 5, 9, 13, 17 and 21 with a follow-up ~4 weeks after last dose.

Outcomes explored pharmacodynamic effects on cognition, affect, memory, temporal perception, executive function, learning, subjective effects, proprioception and balance, plus safety and tolerability measures.

Topics:Healthy Volunteers

Registry

Registry linkNCT04421105