Start
•
Completion

Abuse Potential and Human Pharmacology of Methylone

CompletedResults publishedRegisteredCTG

Double-blind, randomised, placebo-controlled crossover Phase I study (n=17) comparing single oral methylone 200 mg, MDMA 100 mg, and placebo in healthy volunteers to assess abuse potential, subjective and physiological effects, and pharmacokinetics.

Details

Definitive study: double-blind, randomized, placebo-controlled crossover with three experimental sessions per subject (methylone 200 mg, MDMA 100 mg, placebo) following a pilot dose-finding phase.

Primary objectives were to assess abuse potential and subjective/physiological effects; secondary objectives included pharmacokinetic and metabolic characterisation.

Topics:Substance Use Disorders (SUD)

Registry

Registry linkNCT05488171