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Drug Effects on Interpersonal Interaction

CompletedResults publishedRegisteredCTG

This double-blind, placebo-controlled crossover trial (n=30) investigated the effects of MDMA (100mg) compared to placebo on feelings of closeness and mood in semi-structured dyadic conversations.

Details

Paired-partner, within-subject design with three sessions: MDMA+conversation with Person A, placebo+conversation with Person B, and a post-test online session assessing partner preference; drug/placebo order counterbalanced and partners same-sex.

Primary outcomes are self-rated feelings of closeness and connection after each drug session and at the online test; participants are fully debriefed after study completion.

Topics:Healthy Volunteers

Registry

Registry linkNCT05123716