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EEG Characteristics in ECT

Unknown statusRegisteredCTG

Randomised, early-phase diagnostic parallel study (n=11) comparing ketamine versus methohexital induction during ECT, using dcEEG to examine infra-slow/slow-wave characteristics in patients with major depressive episodes.

Details

This pilot, randomized parallel study uses direct current EEG to compare infra-slow wave activity in depressed patients receiving ECT with induction by ketamine versus methohexital.

The aim is to identify dcEEG biomarkers of treatment adequacy (infra-slow wave suppression) that could inform ECT dosing and reduce morbidity; outcomes include dcEEG metrics across sessions and clinical depression severity.

Topics:Major Depressive Disorder (MDD)

Registry

Registry linkNCT04022226