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Effects of MDMA and Methylphenidate on Social Cognition

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Crossover within-subject study (n=30) in healthy volunteers comparing single oral MDMA (75 mg), methylphenidate (40 mg), and placebo to assess effects on emotional and social cognition.

Details

Randomised allocation not specified; crossover within-subject design with three single-dose conditions (MDMA 75 mg, methylphenidate 40 mg, placebo) administered on separate sessions to healthy adult volunteers.

Primary aim is basic science: to compare effects on affective perception and social cognition; outcomes include behavioural tests of emotional and social processing and safety/tolerability monitoring.

Topics:Interpersonal Functioning & Social Connectedness

Registry

Registry linkNCT01616407