Emergency Ketamine Treatment of Suicidal Ideation

Randomised, double-blind, parallel-group trial (n=60) testing intranasal ketamine (0.2 mg/kg given as two doses on admission) versus saline placebo for reduction of suicidal ideation in emergency department patients.

Secondary objectives examine mu-opioid receptor genotypes and correlations of speech and facial movement patterns with reductions in suicidal ideation.