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Investigation of Psychedelic Effects in Psychoactive Substances

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Triple-blind, placebo-controlled, within-subjects study (n=50) testing whether various psychoactive substances (psilocybin, ketamine, DXM, DMT, MDMA, THC) produce experiences similar to classic psychedelics across up to six single-dose sessions.

Details

Randomized, triple-masked, within-subject laboratory study in healthy adult volunteers assessing subjective effects of multiple psychoactive drugs compared with placebo across up to six experimental sessions.

Screening includes medical and psychiatric evaluation, ECG, and routine blood and urine tests. Participants complete two preparation sessions (total 4 hours) prior to the first experimental session and follow-up debrief visits after each dosing session.

Topics:Healthy Volunteers

Registry

Registry linkNCT06772753