Ketamine for Low Mood States in the ER

Open-label, single-group Phase I study in Emergency Department patients (n=14) testing a single IV sub-anaesthetic ketamine dose (0.2 mg/kg over 1–2 minutes) for rapid antidepressant effects and reduction in suicide ideation; patients monitored for 4 hours post-dose.

The published manuscript was later retracted after a Yale investigation found that the protocol-specified doses and the actual delivered doses of ketamine were misrepresented.