Ketamine Treatment of Youth Suicide Attempters

Randomised, triple-blind, placebo-controlled parallel trial (n=140) in inpatient youth (14–30) comparing IV ketamine 0.5 mg/kg infused over 40 minutes every other day to saline; up to six infusions until clinical response or discharge.

All participants receive weekly CAMS psychotherapy starting as an inpatient and continuing outpatient; outcomes include SSI scores, suicidal attempts, readmissions and monthly follow-up for 3 months.