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Ketamine Use in Electroconvulsive Therapy

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Randomised, double-blind, parallel study comparing brief pulse ECT with ketamine infusion (0.5 mg/kg) versus ECT with saline in patients with major depression to assess clinical response and cognitive side effects.

Details

Randomised, double-blind, parallel-group trial comparing brief pulse ECT plus ketamine infusion (0.5 mg/kg) versus ECT plus saline placebo on depressive symptoms.

Secondary outcomes include cognitive impairment, quality of life, BDNF levels and associations with 25-hydroxyvitamin D.

Topics:Major Depressive Disorder (MDD)

Registry

Registry linkNCT02012335