This interventional trial (n=27), led by Maastricht University with sponsorship from the Department of Psychology and Neurosciences, involves exploring the dose-response relationship in LSD-induced subjective and cognitive effects in healthy volunteers.
The present study explores the dose-response relationship in LSD-induced subjective and cognitive effects using single low doses of LSD (5, 10, 20 µg) compared to placebo in healthy volunteers.
Randomised, double-blind, placebo-controlled crossover design with four single-dose sessions per participant; outcomes include validated subjective measures and assessment of cognitive performance.
Randomised, double-blind, placebo-controlled crossover of single low doses of LSD versus placebo.
Single low dose (5 µg).
Single low dose (10 µg).
Single low dose (20 µg).
Matched placebo.