This double-blind, randomized trial (n=60) conducted by Maastricht University Department of Psychology and Neurosciences, explores the effects of repeated doses of LSD (15µg) on mood, cognition, and neuroplasticity in healthy volunteers.
Randomized, double-blind, placebo-controlled trial testing repeated low doses of LSD (15 µg) versus placebo in healthy volunteers over a four-week repeated dosing schedule to assess mood and subjective effects.
Secondary outcomes include measures of cognitive performance and changes in neuroplasticity; safety assessments and standard laboratory screening are used to determine eligibility and monitor adverse events.
Repeated low-dose (microdosing) LSD arm, oral administration over a 4-week repeated dosing schedule.
15 µg per dose; repeated dosing schedule over 4 weeks.
Matched placebo comparator.
Matched placebo, repeated dosing schedule over 4 weeks.