MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Randomized, double-blind, single-site Phase II trial in up to 40 veterans comparing MDMA-assisted therapy versus low-dose d-amphetamine-assisted therapy with 1:1 allocation and stratification by gender.

Procedures include screening and baseline CAPS-5, three preparatory therapy sessions, three experimental dosing sessions (flexible divided doses) each followed by an integration session, and follow-up assessments including CAPS-5 for the primary outcome.