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Neurodynamics of Prosocial Emotional Processing Following Serotonergic Stimulation With N,N-Dimethyltryptamine (DMT) and Harmine in Healthy Subjects

Active not recruitingRegisteredCTG

The aim of the project is to assess brain network dynamics, self-referential information processing and prosociality and learning following the modulation of the serotonin-system by serotonergic-psychoactive compounds.

Details

Randomised, quadruple-blind crossover study in healthy male volunteers (n=34) investigating effects of harmine and DMT on brain network dynamics, self-referential processing and prosocial behaviour.

Three-period crossover comparing harmine+DMT, harmine+placebo (DMT), and double placebo; outcomes focus on neurodynamics, emotion and social-cognitive measures. BMI 18.5–25; German language proficiency required.

Topics:Healthy Volunteers

Registry

Registry linkNCT04716335