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Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)

CompletedRegisteredCTG

This randomised, double-blind, placebo-controlled crossover trial (n=16) investigated the pharmacological interaction between pindolol (20 mg) and MDMA (1.6 mg/kg) in healthy male volunteers, specifically examining effects on cardiovascular function and adverse reactions.

Details

Double-blind, randomised, crossover study in 16 healthy male volunteers testing interactive effects of pindolol (20 mg) given 1 h before a single oral dose of MDMA (1.6 mg/kg).

Outcomes included heart rate, blood pressure, body temperature and adverse-effect profile; procedures included clinical monitoring, ECG and laboratory safety assessments.

Topics:Healthy Volunteers

Registry

Registry linkNCT00895804