Pharmacology of human decision making – Study of the effects of ketamine on healthy volunteers (18-55) making simple perceptual decisions

Randomised, blinded crossover in healthy volunteers comparing a single subcutaneous ketamine injection (0.7 mg/kg) with saline placebo, separated by a one-week washout.

Participants complete baseline and pre/post testing questionnaires and perform a perceptual decision-making task to assess accuracy and effects of ketamine on decision processes.