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Pilot Study of RR-HNK in OCD ((HNKO))

Not yet recruitingRegisteredCTG

This double-blind, placebo-controlled trial (n=45) will study the safety and efficacy of two dosage levels of intravenous (2R,6R)-Hydroxynorketamine (RR-HNK) in adults with obsessive-compulsive disorder (OCD).

Details

The purpose of this study is to understand how RR-HNK works in the brain to bring about a reduction in OCD symptoms.

Randomized, parallel-group, triple-masked Phase I/II trial comparing single IV infusions of 0.25 mg/kg and 0.5 mg/kg RR-HNK versus sterile saline placebo in adults with OCD; EEG and computerized behavioural tests acquired before and after infusion.

Topics:Obsessive-Compulsive Disorder (OCD)

Registry

Registry linkNCT06575075