Start
•Completion
Pilot Study of RR-HNK in OCD ((HNKO))
Not yet recruitingRegisteredCTG
This double-blind, placebo-controlled trial (n=45) will study the safety and efficacy of two dosage levels of intravenous (2R,6R)-Hydroxynorketamine (RR-HNK) in adults with obsessive-compulsive disorder (OCD).
Details
The purpose of this study is to understand how RR-HNK works in the brain to bring about a reduction in OCD symptoms.
Randomized, parallel-group, triple-masked Phase I/II trial comparing single IV infusions of 0.25 mg/kg and 0.5 mg/kg RR-HNK versus sterile saline placebo in adults with OCD; EEG and computerized behavioural tests acquired before and after infusion.
Topics:Obsessive-Compulsive Disorder (OCD)
Registry
Registry linkNCT06575075