Reward Emotion Learning and Ketamine Study

This parallel, randomised, double-blind study in healthy volunteers examines how a single antidepressant dose of ketamine (0.5 mg/kg IV) alters reward-emotion learning and memory compared with placebo.

Participants complete tasks assessing learning about reward and punishment and memory for learned reward associations, with neural measures collected to characterise mechanisms underlying ketamine's antidepressant effects.