The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

Randomised, quadruple-masked, placebo-controlled crossover in healthy adults using two single-dose sessions (psilocybin 15 mg and placebo) with counterbalanced order.

Outcomes include computerised cognitive tasks and MRI/fMRI measures to characterise acute effects on memory, cognition and brain function; basic-science aim to inform safety and therapeutic mechanistic work.