The Effectiveness of Continuous Ketamine Infusion (KONTINUE)

Prospective observational cohort (80 participants) assessing continuous IV ketamine 0.5 mg/kg/day combined with magnesium sulfate 1000 mg/day administered over four days in hospital for chronic pain.

Evaluations scheduled at day 15, 30 and 60 with outcomes focused on pain reduction and safety/tolerability assessments.