Treatment of Suicidal Ideation With Intravenous Ketamine Infusion

Pilot randomised, quadruple-blind, parallel-design study comparing a single IV infusion of ketamine (0.2 mg/kg) versus saline in patients with suicidal ideation and depression; includes cohorts with and without opioid use disorder.

The intervention is given in addition to usual psychiatric care; safety and change in suicidal ideation and depressive symptoms are primary outcomes in this small, proof-of-concept trial.