Non-randomised, parallel interventional study (n=40) testing sequences of HRT, MeRT, ibogaine and 5‑MeO‑DMT in Special Operations Forces veterans with PTSD and cognitive difficulties following TBI.
This interventional programme enrolls 40 SOF veterans with combat deployments, PTSD and cognitive symptoms related to TBI to evaluate sequences of Hormone Replacement Therapy, Magnetic e‑resonance Therapy (MeRT), ibogaine and 5‑MeO‑DMT.
Participants are assigned to one of two parallel sequences delivered by SOC‑F contracted providers; outcomes include changes in PTSD symptoms, cognitive function, objective cognitive tasks and safety/adverse events up to 3‑month follow‑up.
An observational study will run in parallel by the Johns Hopkins Center for Psychedelic and Consciousness Research to further evaluate effectiveness and safety signals.
HRT → Ibogaine + 5‑MeO‑DMT → MeRT sequence delivered by SOC‑F contracted providers.
Hormone Replacement Therapy (HRT) as clinically indicated.
Magnetic e‑resonance therapy (MeRT), EEG‑guided rTMS modality.
Ibogaine with magnesium treatment; dosing per protocol (not specified in registry fragment).
5‑MeO‑DMT administered per protocol (dose not specified).
HRT → MeRT → Ibogaine + 5‑MeO‑DMT sequence delivered by SOC‑F contracted providers.
Hormone Replacement Therapy (HRT) as clinically indicated.
Magnetic e‑resonance therapy (MeRT), EEG‑guided rTMS modality.
Ibogaine with magnesium treatment; dosing per protocol (not specified).
5‑MeO‑DMT administered per protocol (dose not specified).