Trifecta Research Study
Non-randomised, parallel interventional study (n=40) testing sequences of HRT, MeRT, ibogaine and 5‑MeO‑DMT in Special Operations Forces veterans with PTSD and cognitive difficulties following TBI.
Details
This interventional programme enrolls 40 SOF veterans with combat deployments, PTSD and cognitive symptoms related to TBI to evaluate sequences of Hormone Replacement Therapy, Magnetic e‑resonance Therapy (MeRT), ibogaine and 5‑MeO‑DMT.
Participants are assigned to one of two parallel sequences delivered by SOC‑F contracted providers; outcomes include changes in PTSD symptoms, cognitive function, objective cognitive tasks and safety/adverse events up to 3‑month follow‑up.
An observational study will run in parallel by the Johns Hopkins Center for Psychedelic and Consciousness Research to further evaluate effectiveness and safety signals.