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Visual Surround Suppression and Perceptual Expectation Under Psilocybin

RecruitingRegisteredCTG

The prospective study will address the critical need for more precise characterizations of the acute visual effects of the drug psilocybin by measuring the impact of acute psilocybin intoxication on a perceptual task known as visual surround suppression, compared to an active placebo control.

Details

This basic-science, randomized, triple-masked crossover study in healthy volunteers examines acute effects of psilocybin (25 mg) versus active placebo (niacin 100 mg) on visual surround suppression and perceptual expectation.

Data will inform how psilocybin impacts contextual processing and serotonergic contributions to surround suppression, complementing findings in clinical populations and advancing knowledge of human visual neurobiology.

Topics:Healthy Volunteers

Registry

Registry linkNCT04424225