Ketamine infusion monitoring

The manuals converge on close observation during ketamine infusion, with repeated emphasis on monitoring vital signs, watching for acute behavioural or perceptual changes, and confirming medical stability before the participant leaves. They also agree that ketamine is typically delivered as a 40 minute infusion, with several protocols tying monitoring to the infusion window itself and the immediate period afterwards. The sources differ in how much they extend monitoring beyond the infusion. One protocol focuses on continuous vital sign observation and post infusion medical clearance, while another adds ECG monitoring during injection and for 2 hours afterwards. The treatment schedules also vary, with one protocol using a single infusion session in the monitoring description, another using 3 times per week for 2 weeks, and another describing twice weekly dosing in the acute phase. The manuals also differ in the specific adverse effects they foreground. Some emphasise dissociation, perceptual disturbance, sedative or psychotomimetic effects, while others explicitly mention psychotic like symptoms. The cardiac safety extracts broaden the picture further, since they frame ECG or rhythm monitoring as central to detecting abnormalities, which is more specific than the general ketamine infusion monitoring descriptions.