Ketamine is a controlled medicine in Brunei and is permitted for legitimate medical uses (e.g., anaesthesia) under Brunei’s medicines/poisons and narcotics regulatory framework; however, there is no established, reimbursed program for ketamine-based psychiatric (psychedelic/rapid‑antidepressant) treatment comparable to specialist reimbursement schemes seen in some other countries. The Ministry of Health regulates pharmaceuticals and import/registration of medicines via its Pharmaceutical Services unit #; Brunei’s Narcotics Control Bureau enforces the Misuse of Drugs Act for controlled substances #. Regional monitoring and law‑enforcement reporting show ketamine is a substance that appears in local drug seizure reports, consistent with tight controls on distribution outside licensed medical use (see ASEAN/NCB monitoring reports referencing ketamine seizures in Brunei). # #.